Kabita Sharma

Kabita Sharma is a Ph.D. student in the Department of Chemistry at the University of North Texas, USA. Her research focuses on understanding protein degradation mediated by PROTAC (Proteolysis-Targeting Chimera) molecules and on exploring their potential for targeted protein degradation to treat diseases such as cancer. Through this work, she aims to advance drug discovery by targeting previously inaccessible or undruggable sites where PROTAC molecules can operate effectively. Additionally, she is analyzing how the buried surface area of proteins affects their binding and unbinding affinities. Using computational tools, she explores the challenges of removing one infected protein from another during treatment. Driven by a passion for solving complex scientific challenges, Kabita uses her knowledge in chemistry, chemical biology, and computational tools to advance her research. Beyond her academic pursuits, she aspires to inspire others toward science and its wonders through writing and sharing her knowledge.

Bond Cleavage: Homolysis and Heterolysis

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Bond Cleavage

Bond cleavage is the dissolution of a chemical bond (usually a covalent bond). Covalent bond fission, or covalent bond breaking, can occur in two ways: i.e., Homolytic bond cleavage and Heterolytic bond cleavage. Homolytic bond cleavage Homolysis, also known as … Read more

Salt: Preparation, Properties, Types, Uses

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Salt

Salt is defined in chemistry as an inorganic or organic molecule with ionic bonding. When dissolved in water, ions break down into positively charged cations and negatively charged anions. Positive ions (cations) and negative ions (anions) make up salts. Because a … Read more

Acidic Strength of Carboxylic Acids

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Factors Affecting Acidic Strength of Carboxylic Acids

Several factors influence the acidic strength of carboxylic acids. These factors are classified as structural and environmental. Factors Affecting Acidic Strength of Carboxylic Acids The acidic strength of carboxylic acids can be affected by the solvent used. Carboxylic acids tend … Read more

Halogenation of Alkene: Mechanism, Stereochemistry

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Halogenation of alkene

Halogenation of alkene involves the addition of a halogen such as bromine or chlorine to an alkene’s double bond. Because of the polarizability of their covalent bond, halogens can act as electrophiles. Halogen addition is stereospecific, producing vicinal dihalides with anti-addition. … Read more

Different Types of Solvents

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Types of solvents

A solvent is a substance that can combine with other materials to form solutions. Solvents are frequently liquids, although they can also be solids or gases. A solution is a solute-solvent mixture. The amount of substance dissolved in a solvent in a smaller … Read more