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Jyoti Bashyal

Jyoti Bashyal is a Ph.D. student in the Department of Chemistry and Chemical Biology at the University of New Mexico, USA. Her research focuses on understanding the structure-function relationships in glucose transporters (GLUTs) and their implications for diseases such as cancer, diabetes, and metabolic syndromes. By investigating how these proteins work at the molecular level, Jyoti aims to contribute to drug discovery efforts targeting these critical transporters. She is particularly interested in exploring how high-throughput protein expression and crystallization techniques can be applied to better understand carbohydrate-related proteins and their therapeutic potential. Blending her expertise in chemistry, biology, and computational tools, Jyoti is driven by a passion for solving complex scientific challenges. Outside the lab, she is a dedicated science communicator who loves making complex concepts approachable and engaging. Through writing and sharing her knowledge, she hopes to inspire curiosity and excitement about science. Jyoti’s goal is to connect groundbreaking discoveries with real-world impact, encouraging others to see the power and beauty of science in action.

Ion Exchange Chromatography: Principle, Types, Procedure, Applications

January 12, 2023January 10, 2023 by Jyoti Bashyal
Ion Exchange Chromatography

Ion exchange chromatography (IEC), along with ion-partition/interaction and ion-exclusion chromatography, is an important analytical technique for the separation and determination of ionic compounds. This separation is based on ionic (or electrostatic) interactions between ionic and polar analytes, ions in the eluent, … Read more

Size Exclusion Chromatography: Principle, Instrumentation, Applications

January 11, 2023January 9, 2023 by Jyoti Bashyal
Size Exclusion Chromatography

The size-exclusion chromatography (SEC) method, also known as gel-filtration chromatography, separates biological molecules based on their molecular size. It  is not an adsorption technique in comparison to other chromatographic techniques. Size exclusion chromatography is a technique that separates compounds based … Read more

Cope Rearrangement Reaction: Reaction Mechanism, Stereochemistry, Application

January 6, 2023 by Jyoti Bashyal
Cope Rearrangement Reaction

Cope rearrangement of 1,5-dienes is one of the most fundamental C-C bonds-formation reactions available to synthetic chemists today. It is exceptional in the formation of highly stereospecific and predictable C-C  σ -bonds between non functionalized carbon centers. Elizabeth Hardy and Arthur … Read more

Paper Chromatography: Principle, Types, Application, Advantages, Disadvantages

January 4, 2023 by Jyoti Bashyal
Paper Chromatography

Paper chromatography is a simple yet effective detective tool for separating and analyzing the constituents of a mixture. Because paper chromatography is so similar to thin-layer chromatography (TLC), it is often used to teach TLC and other chromatography techniques. It … Read more

Thin layer chromatography: Principle, Components, Procedure, Advantages

January 11, 2023January 3, 2023 by Jyoti Bashyal
Thin layer chromatography

Thin layer chromatography (TLC) is one of the most useful tools in phytochemistry and biotechnology for monitoring the progress of organic chemical reactions and determining the purity of organic compounds. Like all chromatographic methods, TLC uses the analyte’s different affinity … Read more

Aldol Condensation: Definition, Reaction Mechanism, and Applications

December 31, 2022 by Jyoti Bashyal
Aldol Condensation Reaction Mechanism

Aldol condensations are significant in the synthesis of organic compounds because they offer a reliable method for forming carbon-carbon bonds. One of the crucial reactions involving carbonyl compounds (i.e. aldehydes and ketones) is the aldol condensation reaction. The Robinson annulation … Read more

Column Chromatography: Principle, Instrumentation, Types, Procedure, Advantages

December 31, 2022 by Jyoti Bashyal
Column Chromatography: Principle, Instrumentation, Types, Advantages, Disadvantages

Column chromatography is a technique for separating a single chemical compound from a mixture that has been dissolved in a fluid. It separates substances based on the differential adsorption of compounds to the adsorbent as the compounds move through the … Read more

Mass Spectroscopy of Elements – Atomic Structure

December 21, 2022 by Jyoti Bashyal
Mass Spectroscopy of Elements Atomic Structure

Mass spectroscopy of Elements helps for determining the atomic mass of atoms or molecules. It can be used to determine a compound’s relative isotopic abundance, atomic and molecular mass, and structure. A Mass Spectrometry result is a graph that plots … Read more

Electrochemistry: Definition, Types, Components, Examples, Uses

December 23, 2022December 21, 2022 by Jyoti Bashyal
Electrochemistry: Definition, Types, Components, Examples, and Uses

In the modern world, it is challenging to get through a single day without interacting with electrochemistry. An electrochemical reaction provides the necessary energy for any device that requires a battery. Around us, there is a sizable “electric world.” Electricity … Read more

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