Kabita Sharma

Kabita Sharma is a Ph.D. student in the Department of Chemistry at the University of North Texas, USA. Her research focuses on understanding protein degradation mediated by PROTAC (Proteolysis-Targeting Chimera) molecules and on exploring their potential for targeted protein degradation to treat diseases such as cancer. Through this work, she aims to advance drug discovery by targeting previously inaccessible or undruggable sites where PROTAC molecules can operate effectively. Additionally, she is analyzing how the buried surface area of proteins affects their binding and unbinding affinities. Using computational tools, she explores the challenges of removing one infected protein from another during treatment. Driven by a passion for solving complex scientific challenges, Kabita uses her knowledge in chemistry, chemical biology, and computational tools to advance her research. Beyond her academic pursuits, she aspires to inspire others toward science and its wonders through writing and sharing her knowledge.

Glycine- Definition, Preparation, Properties, Uses

August 10, 2022July 23, 2022 by Kabita Sharma

Glycine is a sweet-tasting amino acid obtained from the hydrolysis of protein. It is a nonessential amino acid present in mammals. Mammals can synthesize glycine from the amino acids serine and threonine, and it is also present in certain animal … Read more

Mass Spectrometry (MS)- Instrumentation, Parts, and Steps

January 20, 2023July 19, 2022 by Kabita Sharma

The mass spectrometer is generally designed to perform three basic functions, they are: Instrumentation of Mass Spectrometry (MS) Sample handling system The sample handling system is used to introduce the sample into the ion source at low pressure. Heating is … Read more

Polymers- Definition, Polymerization, Classification, Uses

August 1, 2022July 17, 2022 by Kabita Sharma

Polymer is composed of two Greek words (i.e., poly= many and mer= simple unit). So, polymers are large molecules (macromolecules) formed by the combination of simple units. The simple compounds from which polymers are formed are called monomers. Name of … Read more

Mass Spectroscopy (MS)- Definition, Principle, Parts, Uses

August 19, 2022July 15, 2022 by Kabita Sharma

Mass spectroscopy is the accurate method for determining of molecular mass of the compound and its elemental composition. Principle of Mass Spectroscopy When molecules are bombarded with an energetic electron beam, 1e- is removed from the molecule. The removal of … Read more

UV Spectroscopy- Definition, Principle, Parts, Uses

August 19, 2022July 14, 2022 by Kabita Sharma

UV spectroscopy involves the promotion of electrons (n, σ, π) from the ground state to a higher energy state. In U.V. spectroscopy, the excitation of the electron occurs in the range of 200-800 nm. Principle of UV Spectroscopy When the … Read more

Infrared Spectroscopy- Definition, Principle, Parts, Uses

August 19, 2022July 13, 2022 by Kabita Sharma

Infrared spectroscopy is the measurement of the interaction of IR radiation with compounds. IR region involves the range between region 400-4000 cm-1. IR radiation causes the excitation of molecules from lower to higher vibrational levels. These vibrational levels are associated … Read more

Carboxylic Acids- Structure, Preparation, Properties, Uses

July 11, 2022July 5, 2022 by Kabita Sharma

Carboxylic acids are the organic compounds containing the carboxyl group (-COOH) as a functional group. The general formula is: The name carboxyl is obtained from carbonyl (-CHO) and hydroxyl (-OH) as in the carboxyl group carbonyl and hydroxyl group are … Read more

Esters- Definition, Structure, Preparation, Properties, Uses

July 11, 2022July 2, 2022 by Kabita Sharma

Esters are the derivatives of carboxylic acids containing -COOR as a functional group, in which the -OH group of a carboxylic acid is replaced by the -OR group. Esters are important derivatives of an acid. The ester of a carboxylic … Read more

Aldehyde and Ketone- Structure, Preparation, Properties, Uses

August 20, 2022May 25, 2022 by Kabita Sharma

Aldehyde and ketones are commonly known as carbonyl compounds. Both aldehyde and ketone consist of a carbon-oxygen double bond as a functional group. Which is known as the carbonyl group. The carbonyl group in an aldehyde is bonded to one … Read more