Unimolecular Elimination Reaction (E1 reaction)
An unimolecular elimination reaction is referred to as an E1 reaction. It is a close analog to the SN1 reaction and the opposite of the electrophilic addition reaction. It is … Read more
Kabita Sharma
Qualitative Salt Analysis: Common Ion Effect
Qualitative salt analysis is the process of determining the number of constituents present in an unknown salt sample. The common ion effect is most commonly used in the salt analysis, i.e. … Read more
Common ion effect: Important Applications
Common ion effect refers to the suppression of a weak electrolyte’s degree of ionization by the addition of a strong electrolyte that shares one ion with it. Therefore, the common ion … Read more
Hell Volhard Zelinsky Reaction: Mechanism, Applications, Limitations
Hell Volhard Zelinsky reaction is a halogenation reaction that involves the halogenation of carboxylic acids at the ฮฑ carbon. The reaction is named after the German chemists Carl Magnus von … Read more
HPLC: Principle, Types, Parts, Applications, Advantages, Disadvantages
High performance liquid chromatography (HPLC) technique involves the separation of analytes dissolved in the mobile phase using a particular interaction with a stationary phase. In general, it is a greatly … Read more
Affinity chromatography: Principle, Procedure, Applications, Advantage
Affinity chromatography is a liquid chromatography technique that employs biospecific interactions to separate compounds. The molecule that needs to be purified is selectively and irreversibly adsorbed to a certain ligand. … Read more
Darzens reaction: Definition, Mechanism, Stereochemistry, Synthetic Applications
Darzens reaction is a condensation reaction that involves the reaction of ketone or aldehyde with an ฮฑ-haloester in the presence of a base to form an ฮฑ,ฮฒ-epoxy ester i.e., glycidic … Read more
Haloform Reaction: Definition , Mechanism, Synthetic Applications, Limitations
ย Haloform reaction involves an exhaustive halogenation of a methyl ketone (RCOCH3) in the presence of a base to give a haloform (CHX3).ย Where R can be either a hydrogen atom, … Read more
Favorskii rearrangement: Definition , Mechanism, Synthetic Applications
Favorskii rearrangement involves the conversion of cyclopropanones or ฮฑ -halo ketones to carboxylic acids or their derivatives in presence of the base. Acidic “‘ ฮฑ -hydrogens” must be present in … Read more