Kabita Sharma 
An unimolecular elimination reaction is referred to as an E1 reaction. It is a close analog to the SN1 reaction and the opposite of the electrophilic addition reaction. It is a two-step reaction that typically involves tertiary alkyl halides, though … Read more
Qualitative salt analysis is the process of determining the number of constituents present in an unknown salt sample. The common ion effect is most commonly used in the salt analysis, i.e. qualitative analysis of basic radicals (in group separation). In qualitative … Read more
Common ion effect refers to the suppression of a weak electrolyte’s degree of ionization by the addition of a strong electrolyte that shares one ion with it. Therefore, the common ion effect is used whenever it is necessary to prevent the … Read more
Hell Volhard Zelinsky reaction is a halogenation reaction that involves the halogenation of carboxylic acids at the α carbon. The reaction is named after the German chemists Carl Magnus von Hell and Jacob Volhard and the Russian chemist Nikolay Zelinsky … Read more
High performance liquid chromatography (HPLC) technique involves the separation of analytes dissolved in the mobile phase using a particular interaction with a stationary phase. In general, it is a greatly enhanced form of column chromatography. A solvent is forced through … Read more
Affinity chromatography is a liquid chromatography technique that employs biospecific interactions to separate compounds. The molecule that needs to be purified is selectively and irreversibly adsorbed to a certain ligand. History of Affinity chromatography Immunochemists were the ones who created … Read more
Darzens reaction is a condensation reaction that involves the reaction of ketone or aldehyde with an α-haloester in the presence of a base to form an α,β-epoxy ester i.e., glycidic ester. It is commonly known as Darzens condensation or glycidic … Read more
Haloform reaction involves an exhaustive halogenation of a methyl ketone (RCOCH3) in the presence of a base to give a haloform (CHX3). Where R can be either a hydrogen atom, an alkyl, or an aryl group, and X is a … Read more
Favorskii rearrangement involves the conversion of cyclopropanones or α -halo ketones to carboxylic acids or their derivatives in presence of the base. Acidic “‘ α -hydrogens” must be present in the halo ketones. This reaction is named after the Russian … Read more