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Organic Chemistry

Organic chemistry is a branch of chemistry that examines the structure, characteristics, and interactions of organic molecules that have covalent bonds with carbon.

  • Organic chemistry is a large field due to a critical feature of the element carbon known as carbon catenation. Carbon has a remarkable ability to make extremely stable bonds with other carbon atoms, allowing it to construct stable molecules with relatively complex structures. Catenation is an element’s ability to create bonds with atoms of the same type. As a result, this characteristic of carbon can be used to explain the complexity of organic chemistry.
  • More than a million carbon compounds are known due to their ability in creating covalent bonds. Many are hydrocarbons, which are made up of simply carbon and hydrogen. The majority of hydrocarbons are derived from petroleum.
  • Jöns Jakob Berzelius, a Swedish scientist, used the term “organic” in 1807 to describe chemicals produced by living organisms. Organic molecules were once thought to be impossible to manufacture artificially because they carried a mystical essence of life known as “vital force.”
  • Friedrich Wöhler synthesized the organic chemical urea from inorganic starting materials in 1828, demonstrating that a compound synthesized by living cells could be synthesized in the laboratory without the use of biological starting materials, thus contradicting a basic tenet of vitalism.
  • The synthesis of urea represented the beginning of a new era in organic chemistry, not only redefining the term organic but also rerouting organic chemistry into a wholly new scientific subject.
  • The modern definition of organic is carbon-containing substances, which is now the scientific manner of characterizing the term. However, organic compounds have remained important to every known lifeform over the years, as an abundance of organic molecules comprise all living species.
  • Organic compounds are the foundation of all life on Earth and account for the vast majority of known substances. The variety of organic compounds is structurally complex, and their range of uses is extensive because of the bonding patterns of carbon, which has a valence of four and formal single, double, and triple bonds as well as structures with delocalized electrons.
  • Organic chemistry studies carbon-containing molecules’ structure, characteristics, content, reactions, and production. Most organic molecules comprise carbon and hydrogen but can also contain nitrogen, oxygen, halogens, phosphorus, silicon, and sulfur.
  • Organic chemistry is significant because organic compounds are the majority of the vital biological molecules in living systems. Almost all common polymers are made from organic molecules.
  • They are the foundation or ingredients of many commercial items, including pharmaceuticals, petrochemicals, and agrichemicals, as well as products made from them, such as lubricants, solvents, plastics, fuels, and explosives.
  • Organometallic chemistry, which studies carbon-based molecules including metals, and bioorganic chemistry, which integrates organic chemistry with biochemistry, are two new disciplines of organic chemistry.
  • Organic chemistry methods are applied in pharmaceutical chemistry, natural product chemistry, and materials science. Organic chemists in industry work in both discovery chemistry (creating new chemicals) and process optimization (developing better synthetic methods for large-scale production).

N-Bromosuccinimide(NBS): Preparation, Reactions

September 22, 2023 by Kabita Sharma
N-bromosuccinimide

N-Bromosuccinimide (NBS) is a useful organic chemistry reagent. NBS has traditionally been thought of as a convenient supply of either cationic bromine for electrophilic addition processes or a bromine radical … Read more

Benzoin Condensation: Mechanism, Applications

September 18, 2023 by Kabita Sharma
benzoin condensation

The Benzoin Condensation is a coupling reaction between two aldehydes that produces α-hydroxyketones. Only aromatic aldehydes could be converted using the initial procedures. The condensation of two molecules of benzaldehyde … Read more

Knoevenagel Condensation: Definition, Mechanism, Applications

September 17, 2023 by Kabita Sharma
Knoevenagel condensation

Knoevenagel condensation is the nucleophilic addition of an active hydrogen compound to a carbonyl group, followed by a dehydration process that eliminates a molecule of water. The result is frequently … Read more

Coumarin: Definition, Synthetic processes, Applications

September 7, 2023 by Kabita Sharma
Coumarin synthesis

Coumarin is a naturally occurring substance belonging to the benzopyrone family. It is also known as  1-benzopyran-2-one. Vogel identified the first parent coumarin from tonka bean (Dipteryx odorata) in 1820. The … Read more

Diazotization Reaction: Definition, Mechanism, Applications

September 7, 2023 by Kabita Sharma
Diazotization reaction

Diazotization reaction is the reaction that produces diazonium ions from aromatic amines. The process of creating a diazonium salt or diazonium compound is known as diazotization. An aromatic amine combines … Read more

Sandmeyer Reaction: Mechanism, Applications, Importance, Limitations

September 6, 2023 by Kabita Sharma
Sandmeyer reaction

The Sandmeyer reaction is a form of radical-nucleophilic aromatic substitution process. It’s a valuable tool for replacing an amino group on an aromatic ring with alternative substituents. This reaction converts … Read more

Fischer Esterification Reaction: Mechanism, Applications, Advantages, Limitations

September 5, 2023 by Kabita Sharma
Fischer Esterification Reaction

Fischer Esterification Reaction involves the reaction between an alcohol and carboxylic acid to form an ester. Emil Fischer and Arthur Speier initially explained the reaction process in 1895. Fischer esterification is … Read more

Reductive Amination: Definition, Mechanism, Applications, Limitations

September 5, 2023 by Kabita Sharma
Reductive amination

Reductive amination is the process of conversion of a carbonyl group to an amine through an imine ion intermediate. It is a chemical reaction that converts aldehyde and ketones into … Read more

Gabriel Phthalimide Synthesis: Definition, Mechanism, Applications, Limitations

September 4, 2023 by Kabita Sharma
Gabriel phthalimide synthesis

The Gabriel phthalimide synthesis is a chemical reaction that converts primary alkyl halides to primary amines. It is a nucleophilic substitution process that is mostly utilized to produce primary amines. Siegmund Gabriel, a … Read more

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